Diagnosis of Kaposi's sarcoma requires a biopsy of the lesions.

卡波西诊断需要对病灶进行组织活检。

I remember a young woman who had a sarcoma, and she was 23 years old and had four young children.

我记得一个年轻女人得了，她23岁，有四个孩子。

Ewing's sarcoma can affect a number of different bones, but most commonly affects the femur and the sacrum.

尤因氏可累及许多不同骨骼，但最常股骨与骶骨。

So, classic Kaposi's sarcoma usually affects older males, it's slow growing and it usually affects the legs.

经典型卡波西通常累及老年男，其生长缓慢，一般侵染腿部。

Endemic Kaposi's sarcoma occurs in young adult males who live in Africa and can be more aggressive.

非洲型卡波西常于非洲年轻成年男中，且更具侵袭。

Finally, immunosuppression therapy-related Kaposi's sarcoma affects the skin, and it usually develops following organ transplantation.

最后，免疫抑制相关型卡波西侵染皮肤，通常在器官移植后出现。

Treatment is mainly aimed to stop the progression of Kaposi's sarcoma, as the disease is not curable.

治疗旨在阻止卡波西病程进展，该疾病无法治愈。

Ewing sarcoma is thought to arise from neuroectodermal cells, and which look like small, round, blue cells on microscopy.

尤因认为源于神经外胚层细胞；它们在显微镜下呈现为小、圆形蓝色细胞。

Kate Granger, a 32-year-old doctor suffering from an incurable form of sarcoma, has very strong ambitions for her last hours.

32岁凯特·格兰格一位医生，却身患无法治愈恶肿，她对自己剩下时间有巨大野心。

I was diagnosed with ewing sarcoma bone cancer.

我诊断出患有尤因骨癌。

Specifically, HHV-8 causes Kaposi's sarcoma, a type of cancer usually seen in individuals with AIDS.

具体来说，HHV-8能引起卡波西，一种常于艾滋病患者癌症。

Cohort studies have shown increased risk following non-Hodgkin lymphoma, testicular cancer, uterine sarcomas and head and neck cancers.

队列研究表明，患非霍奇金淋巴、睾丸癌、子宫和头颈癌风险增加。

Epidemic Kaposi's sarcoma is associated with AIDS and can affect many body parts such as skin, mouth, GI tract or lungs.

艾滋病型卡波西与艾滋病相关，会侵染身体多个器官，比如皮肤、口腔、胃肠道或者肺部。

In Ewing sarcoma, X-ray shows lytic bone lesions referred to as onion skin appearance, because the periosteum looks like a sliced onion bulb.

在尤因中，X线显示溶骨病变，称为“洋葱皮样”外观，因为骨膜看起来像一个切开洋葱球。

Kaposi's sarcoma affects most commonly the skin but it can also affect mouth, GI tract and lungs.

卡波西主要侵染皮肤，但也可以侵染口腔、胃肠道与肺部。

Importantly, ectopic expression of c-Fos in H2-c-fosLTR transgenic mice drives osteoblast and chondrocyte proliferation resulting in osteosarcoma and chondrogenic sarcoma.

重要，H2-c-fosLTR转基因小鼠中c-Fos异位表达驱动了成骨细胞和软骨细胞增殖，导致了成骨和软骨形成。

This protein causes defects in the differentiation process of human mesenchymal stem cell and neuroectodermal cells, resulting in Ewing sarcoma tumor cells.

该蛋白在间充质干细胞、神经外胚层细胞分化过程中引起缺陷，产生尤因肿细胞。

Osteosarcoma is linked to RB1 and TP53 genes mutations, while Ewing sarcoma is thought to arise when there are EWSR1, and FLI1 genes mutation.

骨与RB1和TP53基因突变有关，尤因认为源于EWSR1和FLI1基因易位。

Ewing sarcoma is associated with chromosomal mutations, specifically a translocation between the EWSR1 gene on chromosome 22 and FLI1 gene on chromosome 11.

尤因与染色体突变有关，特别22号染色体上EWSR1基因和11号染色体上FLI1基因之间易位。

Now, regardless of type, Kaposi's sarcoma is an endothelial cell neoplasm, so it causes vascular proliferation, resulting in dark or violaceous plaques.

无论何种类型卡波西，都一种内皮细胞，因此它会引起血管增殖，导致黑色或紫色斑块。