In 1999, a patient treated for a rare metabolic disorder at the University of Pennsylvania died.

1999年，一名在宾夕法尼亚大学接受罕见代谢紊乱疾病患者去世。

Other causes include metabolic disorders like nonketotic hyperglycemia; and mutations in the genes coding for normal development of the neurons.

其他原因包括代谢紊乱，如非酮类高血糖症以及编码控制神经元正常发育基因发生突变。

Like what? It could be a metabolic disorder.

比如说？可能是代谢紊乱。

Compromised circadian rhythms are less effective at coordinating organ functioning and can incur health risks like metabolic disorders and vulnerable immune systems.

不稳定生物规律影响器官协调工作，会产生健康风险，像代谢紊乱和免疫系统弱化。

Also, brain imaging (MRI is preferred) can identify potential structural abnormalities, and blood tests can be done to look for underlying metabolic or genetic disorders.

此外，大脑成像（最好是MRI）可以确定潜在结构异常，验血可以寻找潜在代谢或遗传疾病。

Research does suggest that acetic acid can slow down the accumulation of body fat and prevent metabolic disorders in mice and rats.

研究确实表明，乙酸可以内脂肪堆积，并预防小鼠和大鼠代谢紊乱。

Incredibly, this can  affect our body through a dramatic cascade that can lead to metabolic and mood  disorders, and most severely: cancer.

不可思议是， 这种影响会通过一系列连锁反应波及我们身， 可能导致代谢和情绪紊乱，最严重情况下甚至会引发癌症。

This, of course, is an important function. Which is why things can go badly if this process doesn't work properly because of a metabolic disorder, like diabetes.

这当然是一个重要功能。这就是为什么如果这个过程因为代谢紊乱而不能正常工作，比如糖尿病，事情会变得很糟糕。

Heavier individuals tend to have higher blood pressure, higher risks of heart disease, and a greater chance for metabolic disorders like Type 2 diabetes.

较重人往往有较高血压、较高心脏病风险以及较高患 2 型糖尿病等代谢性疾病机会。