So when you lose weight, leptin levels drop.

所以当你减肥的时候，瘦素水平就会下降。

The larger your fat cells are, the more leptin they produce.

脂越大，产生的瘦素就越多。

A couple of the big ones are a hormone called leptin.

几个大的是一种叫做瘦素的荷尔蒙。

That makes sense for leptin, since it's based on the amount of fat you have.

那使得瘦素水平很有意义，因为它基于你所具有的脂量而产生。

One of the most important is leptin, a hormone secreted by your fat cells.

其中最重要的是瘦素，一种由脂分泌的激素。

For example, various hormones like ghrelin, leptin, and insulin affect your hunger and you satisfy the hunger with food.

比如说，种激素，像生长激素释放肤瘦素、胰岛素等会影响你的饥饿感，你会用食物来满足这种饥饿。

" We know from previous research that sleep deprivation causes leptin to drop and ghrelin to rise, so you're hungry."

从先前的研究得知，缺觉会导致瘦素水平下降，饥饿激素水平上升，所以会感到饥饿。”

Its partner, leptin, tells us when we are full.

它的伙伴瘦素会告诉我时候吃饱了。

This extra insulin can make you feel even hungrier as it will block your leptin signal, like we discussed before.

额外的胰岛素会让你感觉更饿，因为它会阻止你的瘦素信号，就像我之前讨论的那样。

Insulin stimulates the body's fat cells to make another hormone called leptin.

胰岛素刺激身体的脂产生另一种叫做瘦素的激素。

This means that leptin levels in the bloodstream decrease.

这意味着血液中的 leptin 水平会下降。

Now, leptin sends a signal of fullness to your brain, so you feel satiated by your food.

现在， 瘦素向您的大脑发送饱腹感信号，让您对食物感到饱足。

The leptin messenger tells the weight-control centre of our brain the status of our current nutrition.

瘦素信使告知我大脑的体重控制中心当前营养状况。

Part of the reason is due to an imbalance in two key appetite-regulating hormones called leptin and ghrelin.

部分原因是由于瘦素和胃饥饿素这两种关键的食欲调节激素失衡所致。

They increase liver fat, upping the risk of cardiovascular disease, and don’t stimulate the hormones insulin and leptin.

它会增加肝脏脂，增加患心血管疾病的风险，并且不会刺激激素胰岛素和瘦素。

The brain is 'blind' to the high leptin levels and therefore to the high fat reserves.

大脑对高水平的瘦素“视而不见”，因此也对高脂储备视而不见。

" The hormone leptin decreases appetite, while the hormone ghrelin increases appetite, " explained Polotsky, who was not involved in the study.

“瘦素会令食欲减退，而饥饿激素则会令食欲增加。

Screen time was also linked to the fluctuations in the levels of leptin- a hormone that controls appetite and influences insulin resistance.

电脑屏幕使用时间也与瘦素水平的波动有关，瘦素是一种控制食欲和影响胰岛素抵抗的激素。

Clinical studies have shown that analogues of amylin can make people sensitive to leptin again, helping them to stop eating earlier.

临床研究显示， 胰岛淀粉样多肽类似物可以让人重新对瘦素产生敏感性，帮助他更早地停止进食。

Leptin levels are high when we are carrying a lot of fat and low when we are slim.

当我体内脂较多时，瘦素水平较高；当我体型苗条时，瘦素水平较低。