A cofactor bound loosely to the apoenzyme and readily separable from it is a coenzyme.

与脱基白结合松弛、易于与之分离的基因。

An enzyme without its cofactor is termed an apoenzyme.

没有助因的酶叫做脱酶。

When a catalytically active enzyme forms a complex with a cofactor a holoenzyme is produced.

酶白和助因两者结合成完整分，成具有活力的全酶。

Some holoenzymes, such as pyruvate dehydrogenase, are highly compex, with several cofactors.

有一些全酶是高度复杂的，如丙酮酸脱氢酶。

Methylmalonic acidemia is an inherited metabolic disorder,which is caused by deficiency of methylmalonyl-coenzyme A mutase or its cofactor adenosylcobalamin.

甲基丙二酸血症是由于甲基丙二酰酶A变位酶或其酶腺苷钴胺素缺陷所致的一种遗传性代谢疾病。