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Randomized aldactone evaluation study (RALES) showed that adding aldosterone antagonist in the treatment of heart failure may decrease 30% mortality of all causes.

随机螺内酯评估研究表明在心力醛甾酮拮抗药可使总死亡率降低30%。

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Osmosis-心血管

Another example is a tumor that produces excess aldosterone, which just like renin, leads to fluid retention.

另一个例子是肿瘤长也会产过多醛固酮一种类似于物质,会导致液体积存。

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Osmosis-内分泌

With these medications around, aldosterone can't exert its effects.

有了这些药物,醛固酮就无法发挥其作用了。

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Osmosis-泌

An important hormone that helps regulate potassium reabsorption or secretion in the kidneys is aldosterone.

中一种帮助调节钾重吸收或分泌重要激素叫醛固酮

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This suggests that people actually following the WHO guidelines are chronically raising their aldosterone.

也就是说,遵循世卫组织关于盐摄入量建议人们,他们体内醛固酮长期处于较高水平

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Osmosis-泌

Other pathological conditions that cause increased aldosterone levels include compensated heart failure and cirrhosis.

其他导致醛固酮水平增加病理状况包括代偿期心衰和肝硬

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Aldosterone has it's purpose, but it's not a hormone you want to regularly have high levels of.

醛固酮有其作用,但在人体中,这种荷尔蒙水平不能太高。

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Osmosis-内分泌

The diagnosis of hyperaldosteronism is mainly done by measuring levels of renin and aldosterone.

醛固酮增多症诊断主要通过测定素与醛固酮水平来完成

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Osmosis-内分泌

Aldosterone is part of a hormone family or axis which work together and are called the renin-angiotensin-aldosterone system.

醛固酮属于一特定激素家族或激素轴一部分,这些激素共同作用,被称为素-血管紧张素-醛固酮系统。

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But, as I mentioned earlier, this renin angiotensin aldosterone system is stimulated by low salt intake.

但是,正如我之前提到,低盐饮食会导致 RAA 系统跃。

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Osmosis-泌

Now, an important hormone that helps regulate potassium reabsorption or secretion in the kidneys is aldosterone.

所以,中有一种重要激素可以帮助调节钾重吸收和分泌,这就是醛固酮

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Osmosis-内分泌

So in this case aldosterone levels are high and renin levels are low in.

因此,在这种情况下,醛固酮水平较高,素水平较低。

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Osmosis-内分泌

Secondary causes of hyperaldosteronism are usually due to excess aldosterone production in response to high levels of renin.

醛固酮增多症继发性原因通常是由于高水平素导致醛固酮成过多。

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As this study shows, a low salt diet increases aldosterone by more than 3 fold in healthy people.

这项研究显示,健康正常人采用低盐饮食,其体内醛固酮水平将增加 3 倍有余。

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High aldosterone is associated with increased inflammation, Chronic kidney disease, Osteoporosis, and cardiovascular disease.

醛固酮水平会增加体内炎症,导致慢性病、骨质疏松症以及心血管疾病。

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WIL启示录

These drugs inhibit Angiotensin Converting Enzyme, hindering an important step in the RAA system resulting in lower aldosterone and lower blood pressure.

这种药物通过抑制血管紧张素转作用(RAA 系统关键作用之一),以达到降低醛固酮水平及血压

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Osmosis-内分泌

Hyperaldosteronism can happen due to primary causes which is where the adrenal gland itself is responsible for the excess production of aldosterone.

醛固酮增多症可以是原发性,即上腺本身产了过量醛固酮

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On the flip side of aldosterone, there is a group of hormones called natriuretic hormones, i. e. sodium urinating hormones.

醛固酮另一面有一组激素叫利钠激素,也就是钠荷尔蒙。

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Another study shows that when salt intake drops below 1.5 teaspoons per day, a significant increase in renin and aldosterone occurs.

另一项研究显示,当盐摄入量降至每天 1.5 茶匙以下,人体中醛固酮及水平将大幅上升。

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Osmosis-泌

Aldosterone increases sodium channels on the lumen side of the principal cell and sodium-potassium pumps on the basolateral side of the principal cells.

它增加主细胞腔面钠离子、钾离子通道和基底面钠-钾泵数量。

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Osmosis-内分泌

Less aldosterone floating around in the blood causes the body to start dumping sodium from the blood into the urine.

血中醛固酮减少使得钠排出增多。

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